The Belmont Report’s distinction between research and the practice of accepted therapy has led various authors to suggest that these purportedly distinct activities should be governed by different ethical principles. We consider some of the ethical consequences of attempts to separate the two and conclude that separation fails along ontological, ethical, and epistemological dimensions. Clinical practice and clinical research, as with yin and yang, can be thought of as complementary forces interacting to form a dynamic system in which the whole (...) exceeds the sum of its parts. Just as effective clinical practice cannot exist without clinical research, meaningful clinical research requires the context of clinical practice. We defend this thesis by triangulation, that is, by outlining how multiple investigators have reached this conclusion on the basis of varied theoretical and applied approaches. More confidence can be placed in a result if different methods/viewpoints have led to that result. (shrink)

A classic work of the European Enlightenment--and one of the most popular, if scandalous, in its day--the Persian Letters captures, in an engaging epistolary format, the transformational spirit of the era. Amid an ongoing tale rife with sex, violence, and wit, the work addresses a diverse range of topics from human nature and the origins of society, to the nature and role of religious belief, the role of women, statecraft, justice, morality, and human identity. With skill and artistry, Raymond (...) MacKenzie’s stunning new translation accurately reflects the mood and character of the work. In his richly conceived Introduction, MacKenzie seamlessly weaves together an overview of the period with details of Montesquieu’s life, including the influences that inspired the _Persian Letters_, the character and power of the book, and its reception. This edition also includes a Calendar of the _Persian Letters_, a Bibliography of Works in English, and a Bibliography of Works in French. Related texts provide insight into the legacy of the _Persian Letters_. They include selections from works by George Lyttelton, Voltaire, Oliver Goldsmith, and Maria Edgeworth. (shrink)

PURPOSE: There is an increasing demand for researchers to provide research results to participants. Our aim was to define an appropriate process for this, based on needs and attitudes of participants. METHODS: A multicenter survey in five sites in the United States and Canada was offered to parents of children with cancer and adolescents with cancer. Respondents indicated their preferred mode of communication of research results with respect to implications; timing, provider, and content of the results; reasons for and against (...) providing results; and barriers to providing results. RESULTS: Four hundred nine parents (including 19 of deceased children) and 86 adolescents responded. Most parents (n = 385; 94.2%) felt that they had a strong right to research results. For positive results, most wanted a letter or e-mail summary (n = 238; 58.2%) or a phone call followed by a letter (n = 100; 24.4%). If the results were negative, phone call (n = 136; 33.3%) or personal visits (n = 150; 36.7%) were preferred. Parents wanted the summary to include long-term sequelae and suggestions for participants (n = 341; 83.4%), effect on future treatments (n = 341; 83.4%), and subsequent research steps (n = 284; 69.5%). Understanding the researcher was a main concern about receiving results (n = 145; 35.5%). Parents felt that results provide information to support quality of life (n = 315; 77%) and raise public awareness of research (n = 282; 68.9%). Adolescents identified similar preferences. CONCLUSION: Parents of children with cancer and adolescents with cancer feel strongly that they have a right to be offered research results and have specific preferences of how and what information should be communicated. (shrink)

Background: Low rates of participation of adolescents and young adults (AYAs) in clinical oncology trials may contribute to poorer outcomes. Factors that influence the decision of AYAs to participate in health research and whether these factors are different from those that affect the participation of parents of children with cancer. Methods: This is a secondary analysis of data from validated questionnaires provided to adolescents (>12 years old) diagnosed with cancer and parents of children with cancer at 3 sites in Canada (...) (Halifax, Vancouver, and Montreal) and 2 in the United States (Atlanta, GA, and Memphis, TN). Respondents reported their own research participation and cited factors that would influence their own decision to participate in, or to provide parental authorization for their child to participate in health research. Results: Completed questionnaire rates for AYAs and parents were 86 (46.5%) of 185 and 409 (65.2%) of 627, respectively. AYAs (n = 86 [67%]) and parents (n = 409 [85%]) cited that they would participate in research because it would help others. AYAs perceived pressure by their family and friends (16%) and their physician (19%). Having too much to think about at the time of accrual was an impediment to both groups (36% AYAs and 47% parents). The main deterrent for AYAs was that research would take up too much time (45%). Nonwhite parents (7 of 56 [12.5%]) were more apt to decline than white parents (12 of 32 [3.7%]; P < .01). Conclusions: AYAs identified time commitment and having too much to think about as significant impediments to research participation. Addressing these barriers by minimizing time requirements and further supporting decision-making may improve informed consent and impact on enrollment in trials. (shrink)

In Britain, policy‐makers tend to view racism as a social attitude rather than an institutional/structural phenomenon. Not until the publication of the MacPherson Report (1999) was the idea of ‘institutional racism’ officially recognised. According to Jules Holroyd, implicit bias as a concept can help us understand and combat the kind of unwitting prejudice the Macpherson report describes. This article explores whether implicit bias is indeed a viable framework for understanding institutional/structural racism. To do so, I bring together Charles Mills’ (...) notion of ‘global white ignorance’ and Lewis Gordon's interpretation of ‘bad faith’. Through Mills’ and Gordon's analyses, which together illuminate both the structural and psychic dimensions of racism I offer an account of the psychodynamics of racism far more consistent with our observations of how racism actually operates in Britain. Specifically, we see that institutional/structural racism is neither unconscious nor is it unmotivated as implicit bias would suggest. As such, I reject implicit bias as a useful or necessary explanatory framework for helping us understand institutional racism as a structural phenomenon. (shrink)

Aron reflects with simplicity and depth on industrial society, communism, the future of democracy, peace and war, the nuclear age, and also Charles de Gaulle, Jean-Paul Sartre, Andre Malraux, Henry Kissinger and others.

This study analyzes a series of complex, ambivalent literary responses to the decades of civil turmoil in seventeenth-century England that simultaneously demanded public commitment and prompted private withdrawal. From their various perspectives the Royalist writers raised in the humanist tradition are shown to appreciate anew the value of patient fortitude.

ISBN 0-7914-3529-6 (hard : alk. paper). — ISBN 0-7914-3530-X (pbk. : alk. paper ) 1. Dewey, John, 1854-1952. I. Title. II. Series: SUNY series in philosophy of education. B945.D4B65 1997 191— dc 21 96-52291 CIP 10 987654321 For Jayne ...

In lieu of an abstract, here is a brief excerpt of the content:“Reason and Religion”: The Science of AnglicanismRaymond D. TumblesonThis essay explores a rhetoric of “reason” in Anglican anti-Catholic polemics during the short and turbulent reign of James II. This reign witnessed an intense propaganda battle between Catholic and Anglican pamphleteers because the former for the first time in over a century were permitted openly to put their case, and in response the latter defended their doctrine and status as (...) the established church with a new urgency. For the first time, the possibility, feared by English Protestants and hoped for by Catholics, that given encouragement many people would convert to Catholicism, “the most conspicuous deviant element in society,” seemed credible, although, unsurprisingly given the brevity of James’s rule, both hope and fear proved groundless. 1 In addition to reiterated claims to have scripture and antiquity on their side, apologists for the Church of England offered a third and clinching argument against Catholicism—that reason itself was with them. They saw no contradiction between what Richard Sherlock calls a “scripture-based argumentative framework” and “the priority of natural reason.” 2 In A Rational Account of the Grounds of Protestant Religion Edward Stillingfleet developed what would become the predominant Anglican theological case against Catholicism twenty years later, when he endorsed “the judgement of Sense” as the means to a “certainty “ independent of the Papal “Infallibility “ that “Destroy[s] the obligation to Faith which ariseth from the rational evidence of Christian Doctrine.” 3 Far from mutually [End Page 131] exclusive, Protestantism and reason seemed naturally complementary, even identical, to Anglican polemicists: only Popery, in its superstition, idolatry, and implicit faith, was antagonistic to reason. As Richard W. F. Kroll observes, the “defense of contingency, premised on a skeptical empiricism, becomes not the chief discourse of dissent but, again, its opposite: the language of the most visible institutions returned to power after the Restoration.” 4 Reason and the Anglican monopoly of worship are consistently identified by Anglican apologists of the 1680s, and Popery threatens both.What Terry Eagleton has called “the Enlightenment dream of a world entirely transparent to reason, free of the prejudice, superstition and ob-scurantism of the ancien regime” has unacknowledged antecedents in Protestant polemics against “the prejudice, superstition and obscurantism” of Catholicism. 5 This essay examines the differences between the polemical literatures of the reigns of Charles II and James II, the ways in which “reason” becomes an important force against Catholicism, and the method in which this usage entangles anti-Catholicism in the construction of modern science. In 1685, the year of James’s coronation, John Williams argued that religious services ought to be conducted “in a Tongue understood of the people,” recommending that “we consult the reason of the thing.” 6 In attacking Catholicism, Anglican theologians redefined religion itself as based more on reason than on faith, because Papists could lay equal claim to faith, but only the Church of England possessed reason as they defined it. Stillingfleet’s theological career is paradigmatic for Restoration Angli-canism’s enlistment of reason in sectarian disputes: his Originae Sacrae (1662) defends Christianity as rational, then in 1665 A Rational Account of the Grounds of Protestant Religion narrows religious rationality to exclude Catholicism; in the wake of the Exclusion Crisis, the 1681 The Unreasonableness of Separation chides Dissenters for being “unreasonable” because they do not conform to the Church of England; and finally in 1687 The Doctrine of the Trinity and Transubstantiation Compared, as to Scripture, Reason, and Tradition returns to the subject of A Rational Account, tightening its six hundred learned pages into colloquial propaganda aimed at lay readers. 7 In the clear light of reason, where the only static—in Michel [End Page 132] Serres’s sense—is corruption, disagreement (with Anglicanism) becomes impossible. 8This paper examines sectarian polemics in order to approach the relation between science, the paradigmatic modern intellectual structure, and theology, the paradigmatic premodern intellectual sructure, from an unaccustomed angle. The immense wave of propagandistic Anglican theologizing under James II establishes the superiority of the Church of England to Rome by re-borrowing the methods and conventions of rationality which scientific experimentalism itself had originally derived from theology. 9 In these tracts... (shrink)

After examining c.s. peirce's concept, taxonomy, and hierarchy of the theoretical sciences of discovery as well as his notion of the economy of research as an objective of science, a study is made of his occasional but distinct use of the term 'system' in conceptual and procedural contexts. the study shows that peirce's views on systems theory resemble current views held by some proponents of the systems concept and the systems approach to problem-solving.

Within the Aristotelian tradition of the Latin Middle Ages ‘scientific knowledge’ was understood as knowledge derived from the conclusions of syllogism that deals with what is necessary and unchanging. According to Aristotle, however, the ‘arts’, which deal with doing and making, were not seen as ‘sciences’, because they deal with what is ‘contingent’. In his famous Ars lulliana Raymond Lull also wants to understand the productive ‘arts’ as demonstrative ‘sciences’ – he describes here a transcendental practical method, which is (...) intented to imitate God’s great work of art as creator. Even so, the Ars does not treat an abstract, Aristotelian science, but one that deals with creative production. Such a science should not be limited to universals, but also include the concrete individuals. Whereas the scholastics tried to take all the different disciplines as Aristotelian ‘sciences’, Lull wanted to take all the disciplines as ‘artes’. Here, therefore, it seems we have an anticipation of the change from the scientific paradigm of the Middle Ages to the arts model of the Renaissance. (shrink)

The eminent French biologist and historian of biology, François Jacob, once notoriously declared “On n’interroge plus la vie dans les laboratoires”: laboratory research no longer inquires into the notion of ‘Life’. Nowadays, as David Hull puts it, “both scientists and philosophers take ontological reduction for granted… Organisms are ‘nothing but’ atoms, and that is that.” In the mid-twentieth century, from the immediate post-war period to the late 1960s, French philosophers of science such as Georges Canguilhem, Raymond Ruyer and Gilbert (...) Simondon returned to Jacob’s statement with an odd kind of pathos: they were determined to reverse course. Not by imposing a different kind of research program in laboratories, but by an unusual combination of historical and philosophical inquiry into the foundations of the life sciences (particularly medicine, physiology and the cluster of activities that were termed ‘biology’ in the early 1800s). Even in as straightforwardly scholarly a work as La formation du concept de réflexe aux XVIIe et XVIIIe siècles (1955), Canguilhem speaks oddly of “defending vitalist biology,” and declares that Life cannot be grasped by logic (or at least, “la vie déconcerte la logique”). Was all this historical and philosophical work merely a reassertion of ‘mysterian’, magical vitalism? In order to answer this question we need to achieve some perspective on Canguilhem’s ‘vitalism’, notably with respect to its philosophical influences such as Kurt Goldstein. (shrink)

This volume consists of autobiographical by the following scholars, together with pictures and autographs: Raven I. McDavid, Jr., Henry M. Hoenigswald, John B. Carroll, William G. Moulton, Archibald A. Hill, Yakov Malkiel, Charles F. Hockett, Harold B. Allen, William Bright, Einar Haugen, George S. Lane, Frederic G. Cassidy, James B. McMillan, Winfred P. Lehmann, Fred W. Householder, and Dell Hymes. A master list of references, and an index of persons conclude the volume.

Contents: John A. HALL and Ian JARVIE: Preface. John A. HALL and Ian JARVIE: The Life and Times of Ernest Gellner. PART 1 INTELLECTUAL BACKGROUND. Ji_i MUSIL: The Prague Roots of Ernest Gellner's Thinking. Chris HANN: Gellner on Malinowski: Words and Things in Central Europe. Tamara DRAGADZE: Ernest Gellner in the Soviet East. PART 2 NATIONS AND NATIONALISM. Brendan O'LEARY: On the Nature of Nationalism: An Appraisal of Ernest Gellner's Writings on Nationalism. Kenneth MINOGUE: Ernest Gellner and the Dangers of (...) Theorising Nationalism. Anthony D. SMITH: History and Modernity: Reflection on the Theory of Nationalism. Michael MANN: The Emergence of Modern European Nationalism. Nicholas STARGARDT: Gellner's Nationalism: The Spirit of Modernisation? PART 3 PATTERNS OF DEVELOPMENT. Peter BURKE: Reflections on the History of Encyclopaedias. Alan MACFARLANE: Ernest Gellner and the Escape to Modernity. Ronald DORE: Sovereign Individuals. Shmuel EISENSTADT: Japan: Non-Axial Modernity. Marc FERRO: l'Indépendance Telescopée: De la Décolonisation a l'Impérialisme Multinational. PART 4 ISLAM. Abdellah HAMMOUDI: Segmentarity, Social Stratification, Political Power and Sainthood: Reflections on Gellner's Theses. Henry MUNSON, Jr.: Rethinking Gellner's Segmentary Analysis of Morocco's Ait cAtta. Jean BAECHLER: Sur le charisme. Charles LINDHOLM: Despotism and Democracy: State and Society in the Premodern Middle East. Henry MUNSON, Jr.: Muslim and Jew in Morocco: Reflections on the Distinction between Belief and Behavior. Talal ASAD: The Idea of an Anthropology of Islam. PART 5 SCIENCE AND DISENCHANTMENT. Perry ANDERSON: Science, Politics, Enchantment. Ralph SCHROEDER: From the Big Divide to the Rubber Cage: Gellner's Conception of Science and Technology. John DAVIS: Irrationality in Social Life. PART 6 RELATIVISM AND UNIVERSALS. John SKORUPSKI: The Post-Modern Hume: Ernest Gellner's 'Enlightenment Fundamentalism'. John WETTERSTEN: Ernest Gellner: A Wittgensteinian Rationalist. Ian JARVIE: Gellner's Positivism. Raymond BOUDON: Relativising Relativism: When Sociology Refutes the Sociology of Science. Rod AYA: The Devil in Social Anthropology; or, the Empiricist Exorcist; or, the Case Against Cultural Relativism. PART 7 PHILOSOPHY OF HISTORY. William MCNEILL: A Swan Song for British Liberalism? Andrus PARK: Gellner and the Long Trends of History. Eero LOONE: Marx, Gellner, Power. Rosaire LANGLOIS: Coercion, Cognition and Production: Gellner's Challenge to Historical Materialism and Postmodernism. Ernest GELLNER: Reply to Critics. Ian JARVIE: Complete Bibliography of Gellner's Work. Name index. Subject index. (shrink)

Raymond Aron and his Dialogues in an Age of Ideologies examines the thought and rhetoric of the most interesting thinker of the twentieth century of whom no one has heard. This book investigates Raymond Aron's conversations on politics during the Cold War with several of his more well-known interlocutors including Jean-Paul Sartre, Friedrich Hayek, and Charles de Gaulle. Through exploring these dialogues on the subjects of Marxism, freedom, and nationalism, we see the prudence of Aron's politics of (...) understanding as well as the emphasis he places on and virtue he demonstrates in public discourse. Through his dialogues, Aron shows us not only how to think politically but also how to engage in constructive public debate. He stands as a model for us to emulate in our own age of ideologies. (shrink)